Meet the Izzards: part one, BBC One, review - Telegraph
Michael Deacon reviews the first part of Meet the Izzards, a BBC One documentary in which comedian Eddie Izzard traces his family's history. Meet the Izzards is a two-part BBC One documentary in which actor and comedian Eddie Izzard uses genetics to trace From Wikipedia, the free encyclopedia. Meet the Izzards is a two-part BBC One documentary in which actor and comedian Eddie Izzard uses genetics to trace his distant ancestry. The first part titled.
We were told that the most up-to-date research from a team of researchers at the University of Copenhagen had found that everyone with blue eyes can be traced back to one person who lived on the Black Sea coast 10, years ago.
- Eddie Izzard
- Oh no, there's been an error
This appears to be a reference to the study by Eiberg et al which discovered a set of SNPs in " blue-eyed individuals from Denmark, and in 5 and 2 blue-eyed individuals from Turkey and Jordan" that were suggestive of a common founder mutation. It is therefore somewhat premature to draw conclusions at this stage on the geographical origin of a specific trait.
The next stage of the journey took Eddie to Istanbul on the pretext that his ancestors would most likely have travelled to Europe across the Bosphorous Straits, the narrow stretch of water which separates Asia and Europe.
It transpired that Eddie's parents spent their honeymoon in Istanbul, and he was given the opportunity to stay in the very same room that they shared.
He was then whisked off to Pompeii where he was introduced to the skeletons of some of his "genetic cousins" who died in 79 AD after the eruption of Mount Vesuvius. Geneticists were able to extract DNA from the teeth of the skeletons. Although not explained very clearly in the programme the reason for the diversion to Pompeii is that some of the skeletons were thought to belong to haplogroup T2b, a sister branch of Eddie Izzard's own mtDNA haplogroup.
The letters T2f2a1 flashed up on the screen and although the word haplogroup was not mentioned these letters referred to Eddie Izzard's haplogroup assignment. A test covering such a small number of markers is not going to be sufficient to provide such a detailed haplogroup assignment so we must presume that the mtDNA testing was not done by BritainsDNA.
Eddie Izzard was told that T2f21a confusingly described as a "marker" dates back about years, or fewer than 70 generations ago. Jim Wilson then went on to inform Eddie that his "mother's mother's mother's people were Vikings".
Meet the Izzards
Eddie was promptly despatched to a Viking port in Denmark to meet a Danish brother and sister who share his marker or more specifically his T2f21a haplogroup. A somewhat absurd conversation followed whereby Eddie and the two Danes tried to find some traits and interests in common.
As Eddie and the Dane are only very distantly related through their mitochondrial DNA any traits they share in common will be purely by chance rather than through a shared genetic inheritance.
Continuing with the Viking theme Eddie was put into a replica Viking longboat to recreate the journey his supposed Viking ancestors would have made to Britain. Haplogroups do tend to cluster in specific geographical locations but the mtDNA of living people is not necessarily representative of the DNA of past populations, and it is simply not possible to determine that a specific ancestor from years ago was a Viking, a Norman, a Celt or any other such tribe.
Jim Wilson also conveniently overlooked the fact that there was no such group known as the Vikings years ago! Only four matches were found.
We were informed that they shared a maternal line ancestor within the last to years. However, Eddie was told that he has a "unique motherline marker" so I presume that his sequence was not an exact match with that of the sisters. With one mismatch the common ancestor could have lived well over years ago. Nevertheless, Eddie proceeded to share a cup of tea with the sisters while they discussed their shared "Viking" heritage.
The sisters had considered themselves to be Anglo-Saxons and were therefore somewhat surprised to be told that they were "Vikings"!
It is a pity that they were not informed that if you go back just a few thousand years we all have so many ancestors that we will invariably have multiple ancestors who were Vikings, Anglo-Saxons or indeed any other group that takes our fancy. Meet the Izzards Part 2: The Dad's Line The second programme began with Eddie visiting his father in Bexhill-on-Sea and reviewing his father's genealogical research.
The Izzard line has been traced back to the 17th century to a William Izard who married Mary Dalloway in Darlington in Eddie's father was hoping that the DNA testing would help to take the family tree further back in time. The focus would be on the "significant markers" in Eddie's Y-chromosome which would determine the key points in Eddie's "journey" through his fatherline.
SNP is an abbreviation for single-nucleotide polymorphism, and it is the SNPs which define the branches of the human Y-chromosome tree. The Y-SNP tree is now a very large and complicated structure, which is in a constant state of flux.
Their size is believed to be an adaptation to the dense vegetation and low ultraviolet light in the forest. The Bakola were chosen to represent haplogroup A which, at the time the programme was made, was the most ancient branch on the human Y-DNA tree. We were told that Y-chromosome Adamthe most recent common ancestor of all living men, dates back aroundyears ago.
This date is derived from a paper published by Cruciani et al in Jim Wilson, the programme's consultant, might not have known about the imminent publication of this paper. However, if the BBC had done what they should have done and sought a range of opinions from leading population geneticists, they might well have learnt in advance of this important change in the Y-tree as the findings would no doubt have been discussed at scientific meetings. Michael Hammer, one of the co-authors of the paper.
Meet the Izzards (TV Series – ) - IMDb
However, regardless of the date of Y-chromosome Adam it really would have made no difference whether Eddie had visited the Bakola or the Mbo people because the present-day location of a haplogroup is unlikely to coincide with its point of origin several hundred thousand years ago. As Mendez et al remind us, the finding of haplogroup A00 "underscores how the stochastic [random] nature of the genealogical process can affect inference from a single locus and warrants caution during the interpretation of the geographic location of divergent branches of the Y chromosome phylogenetic tree for the elucidation of human origins".
This event was thought to have occurred over 60, years ago, and provided an excuse to send Eddie Izzard off to Dubai in the United Arab Emirates, where he had a meeting in an exclusive hotel with archaeologist Jeff Rose who discussed with him the latest archaeological findings from Arabia.
A big population explosion is thought to have occurred around 50, years ago at which point humans began to spread out from Arabia. Eddie was taken to meet a year-old man in Dubai who has been responsible for his own mini-population explosion having fathered 93 children to date by four wives.
His youngest child was just nine months old, but he has two more children on the way and plans to go on until he has children, despite having recently lost a leg in a car accident.
This clip can be seen on YouTube. Given that the programme was supposed to investigate Eddie Izzard's male line it was somewhat confusing to digress into a discussion of Neanderthal DNA. Izzard appeared in literature to support changing the British electoral system from first-past-the-post to alternative vote for electing Members of Parliament to the House of Commons in the Alternative Vote referendum in During his time at the university he established the now-defunct Alternative Productions Society in the Union of Students with the aim of promoting fringe-based arts.
During an interview for the Stripped tour, he spoke about becoming more active in European politics as well as running for political office in Europe within the next decade.
Izzard added a stop in New Orleans during his Stripped tour. In Septemberhe declared his ambition to stand for the party in the future as an MPMEPor Mayor of London announcing an intention to stand for the London mayoral election in He ran from London to Cardiff to Belfast to Edinburgh and back to London, carrying the flag of the country — England, Scotland, or Wales — in which he was running. In Northern Ireland he carried a self-designed green flag bearing a white dove.
The blog Eddie Iz Running documented his 43 marathons in 51 days, covering at least 27 miles per day totaling more than 1, milesending on 15 September Izzard completed his first marathon on 23 February. He attempted such a project in South Africa inbut withdrew with health concerns. Because he had spent one day in hospital, he had to run two consecutive marathons on this last day.
He believes in what he says.
Izzard automatically replaced her and served until the next NEC election, held in summer The website has gone through several branding changes since it was launched, originally named BBC Online, it was then rebranded as BBCi before being named bbc.
It was then renamed BBC Online again inhowever the service uses the branding BBC, the web-based service of the BBC is one of the most visited websites and the worlds largest news website. As ofit contained two million pages.
Inthe BBC bought the www.
The navbar was designed to offer a similar system to the i-bar on BBCi interactive television. Interactive TV services continued under the BBCi brand until it was dropped completely inthe BBCs online video player, the iPlayer has, however, retained an i-prefix in its branding. The widget-based design was inspired by such as Facebook and iGoogle. The new homepage also incorporated the design used in the s on the BBCs television service into the large header.
Meet the Izzards - WikiVisually
On 30 Januarya new design became available as a beta version. This homepage expanded on the idea and the customisation theme 6.
Sleigh in as The Daily Telegraph and Courier, the papers motto, Was, is, and will be, appears in the editorial pages and has featured in every edition of the newspaper since April 19, The paper had a circulation ofin December and its sister paper, The Sunday Telegraph, which started inhad a circulation ofas of December The Daily Telegraph has the largest circulation for a newspaper in the UK.Eddie Izzard - Full Interview on Alan Carr: Chatty Man
The two sister newspapers are run separately, with different editorial staff, but there is cross-usage of stories, articles published in either may be published on the Telegraph Media Groups www. However, critics, including an editor, accuse it of being unduly influenced by advertisers. Joseph Moses Levy, the owner of The Sunday Times, agreed to print the newspaper, the paper cost 2d and was four pages long.
Nevertheless, the first edition stressed the quality and independence of its articles and journalists, however, the paper was not a success, and Sleigh was unable to pay Levy the printing bill.
Levy took over the newspaper, his aim being to produce a newspaper than his main competitors in London. The same principle should apply to all other events—to fashion, to new inventions, inJules Verne published his novel Michael Strogoff, whose plot takes place during a fictional uprising and war in Siberia.
Inthe newspaper absorbed The Morning Post, which espoused a conservative position. In Novemberwith Fleet Street subjected to almost daily bombing raids by the Luftwaffe, The Telegraph started printing in Manchester at Kemsley House, Manchester quite often printed the entire run of The Telegraph when its Fleet Street offices were under threat.
During the Second World War, The Daily Telegraph covertly helped in the recruitment of code-breakers for Bletchley Park, the ability to solve The Telegraphs crossword in under 12 minutes was considered to be a recruitment test.
Meet the Izzards: part one, BBC One, review
The competition itself was won by F. Hawes of Dagenham who finished the crossword in less than eight minutes, both the Camrose and Burnham families remained involved in management until Conrad Black took control in 7.
Human mitochondrial genetics — Human mitochondrial genetics is the study of the genetics of human mitochondrial DNA. The human mitochondrial genome is the entirety of information contained in human mitochondria. Mitochondria are small structures in cells that generate energy for the cell to use, Mitochondrial DNA is not transmitted through nuclear DNA. In humans, as in most multicellular organisms, mitochondrial DNA is inherited only from the mothers ovum, there are theories, however, that paternal mtDNA transmission in humans can occur under certain circumstances.
Mitochondrial inheritance is therefore non-Mendelian, as Mendelian inheritance presumes that half the material of a fertilized egg derives from each parent. Eighty percent of mitochondrial DNA codes for mitochondrial RNA, and therefore most mitochondrial DNA mutations lead to functional problems, which may be manifested as muscle disorders. Because they provide 30 molecules of ATP per glucose molecule in contrast to the 2 ATP molecules produced by glycolysis, the mitochondrial diseases are genetic disorders carried in mitochondrial DNA, or nuclear DNA coding for mitochondrial components.
Slight problems with any one of the enzymes used by the mitochondria can be devastating to the cell. In humans, mitochondrial DNA forms closed circular molecules that contain 16, DNA base pairs, each human mitochondrion contains, on average, approximately 5 such mtDNA molecules, with the quantity ranging between 1 and Each human cell contains approximately mitochondria, giving a number of mtDNA molecules per human cell of approximately Mitochondrial genetic mutations that occur in the nuclear DNA can occur in any of the chromosomes, mutations inherited through the chromosomes can be autosomal dominant or recessive and can also be sex-linked dominant or recessive.
Chromosomal inheritance follows normal Mendelian laws, despite the fact that the phenotype of the disease may be masked, because of the complex ways in which mitochondrial and nuclear DNA communicate and interact, even seemingly simple inheritance is hard to diagnose.
A mutation in chromosomal DNA may change a protein that regulates the production of another protein in the mitochondria or the cytoplasm. However, if a male has a trait, no offspring inherit it. In a few cases, some mitochondria or a mitochondrion from the cell enters the oocyte.
Genes in the mitochondrial genome are as follows.